Human Albumin

Drug Type
 Generic Drug
Medicine System
 Allopathy
Drug Availability
 Unspecified

Albumin Monograph

Pregnancy Category C

Essential Medicine :

Usage / Indications

Burns, hypoproteinaemia, shock, hypovolemia, acute liver failure, dialysis.

Dosage

Source : NFI National Formulary of India
Intravenous infusionFor hypovolemia

  • Adult- 25g,Child- 1g/kg.Max.- 2g of 20%/kg body weight.

For hypoproteinaemia

  • Adult- 2g/kg daily.Usual rates of infusion: up to 5 ml/min (5%) or1 to 2 ml/min (20%).

Contraindications

  • Congestive heart failure, severe anaemia, history of allergic reactions to human albumin
  • Pregnancy

Precautions

  • If dehydration is present additional fluid must follow the administration of albumin. 
  • Administration of albumin should be supplemented or replaced by packed red blood cells, history of cardiac or circulatory disease, increased capillary permeability. 

Side Effects / Adverse Effects

Allergic (or) pyrogenic reactions, tachycardia, rash, anaphylactic shock, increased salivation.

Storage

  • Store protected from light at a tempreture between 2-25⁰C.
  • Human albumin stored at 2-8⁰C may be expected to continue to meet the requirements of the monograph for five years from the date on which it was heated at at 60⁰C for 10 hours.
  • Human albumin stored at a temperature not exceeding 25⁰C may be expected to meet the requirements of the monograph for three years from the date on which it was heated at 60⁰C for 10 hours. 

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